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KMID : 0355220120370040189
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Journal of Korean Academy Oral Medicine
2012 Volume.37 No. 4 p.189 ~ p.193
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Oral Pigmentation Resulting from Pharmacological Treatment in Patient with Chronic Hepatitis C
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Kim Young-Gun
Ahn Hyung-Joon
Choi Jong-Hoon
Kwon Jeong-Seung
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Abstract
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Oral pigmentation has numerous etiologies. It can be associated with congenital diseases and syndromes, certain acquired diseases, and systemic medications. Pigmented lesions caused by serious disease such as melanoma should be diagnosed correctly, because it would be fatal. For appropriate differential diagnosis, clinicians should know about the etiologies causing oral pigmentation and take patients history carefully. Biopsies would be necessary for histopathological findings. Close follow up for clinical symptoms are also necessary. In this case report, we presented a case of oral hyperpigmentation in Asian patient who was receiving pegylated interferon and ribavirin combination therapy for hepatitis C virus infection.
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KEYWORD
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Hepatitis C virus, Oral hyperpigmentation, Interferon, Ribavirin
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